Factor V Leiden

    Factor V Leiden is an inherited disorder of blood clotting. It is a variant of human factor V that causes a hypercoagulability disorder. In this disorder, the Leiden variant of factor V cannot be inactivated by activated protein C. Factor V Leiden is the most common hereditary hypercoagulability disorder amongst Eurasians. It is named after the city Leiden, where it was first identified in 1994 by Prof R. Bertina et al.

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